Under the 2015 licensing agreement with Kuros, Checkmate is investigating vidutolimod (CMP-001), an advanced generation Toll-like receptor 9 (TLR9) agonist, delivered as a biologic virus-like particle utilizing a CpG-A oligodeoxynucleotide as a key component, across multiple tumor types in combination with several checkpoint inhibitor immunotherapies. Checkmate is conducting multiple clinical trials, including two phase 2 trials in the melanoma indication, which have already triggered two milestone payments of $2 and $4 million by Checkmate earlier this year. These milestone payments together with the payment from the royalty purchase agreement announced today amount to $13 million in revenue to Kuros in 2021.

Joost de Bruijn, Chief Executive Officer of Kuros, commented: “This transaction with XOMA offers a unique opportunity for Kuros to secure meaningful capital, while keeping significant downstream payment potential upon successful development of vidutolimod by Checkmate. The proceeds will allow Kuros to further invest in our core business, including commercialization of our MagnetOs bone graft and the clinical development of Fibrin-PTH, which is a substantial commercial opportunity.”

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